H&E section of a bovine fibropapilloma. Viruses in the delta genus, such as BPV1, cause fibropapillomas in ungulates. The virus infects and replicates in dermal fibroblasts causing extensive proliferation and a large fibroma underlying the epithelium. The overlying epithelium shows papillomatosis, acanthosis, koilyocytosis, parakeratosis and hyperkeratosis.
Author: Baker
Credit: Carl Baker. This image is the work of an National Institutes of Health employee, taken or made as part of that person's official duties. As a work of the U.S. federal government, the image is in the public domain.
