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Legend
L1 Pentamers
L1 Monomers
L2
DNA
Histone H2A
Histone H2B
Histone H3.3
Histone H4
Histone H3.1
Acetyl Group
Methyl Group
Lysine Residue
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References
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Cerqueira, C., Schiller, J.T., (2017). Papillomavirus assembly: An overview and perspectives. Virus research 231, 103-107. doi 10.1016/j.virusres.2016.11.010
Day, P.M., Schelhaas, M., (2014). Concepts of papillomavirus entry into host cells. Curr Opin Virol 4, 24-31. doi 10.1016/j.coviro.2013.11.002
DiGiuseppe, S., Bienkowska-Haba, M., Guion, L.G., Sapp, M., (2017). Cruising the cellular highways: How human papillomavirus travels from the surface to the nucleus. Virus research 231, 1-9. doi 10.1016/j.virusres.2016.10.015
Goetschius, D.J., Hartmann, S.R., Subramanian, S., Bator, C.M., Christensen, N.D., Hafenstein, S.L., (2021). High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility. Sci Rep 11, 3498. doi 10.1038/s41598-021-83076-5
Guan, J., Bywaters, S.M., Brendle, S.A., Ashley, R.E., Makhov, A.M., Conway, J.F., Christensen, N.D., Hafenstein, S., (2016). Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site. Structure. doi 10.1016/j.str.2016.12.001
Guion, L.G., Sapp, M., (2020). The Role of Promyelocytic Leukemia Nuclear Bodies During HPV Infection. Front Cell Infect Microbiol 10, 35. doi 10.3389/fcimb.2020.00035
Joyce, J.G., Tung, J.S., Przysiecki, C.T., Cook, J.C., Lehman, E.D., Sands, J.A., Jansen, K.U., Keller, P.M., (1999). The L1 major capsid protein of human papillomavirus type 11 recombinant virus-like particles interacts with heparin and cell-surface glycosaminoglycans on human keratinocytes. J.Biol.Chem. 274, 5810-5822. doi 10.1074/jbc.274.9.5810
McBride, A.A., (2021). Human papillomaviruses: diversity, infection and host interactions. Nat Rev Microbiol. doi 10.1038/s41579-021-00617-5
Porter, S.S., Liddle, J.C., Browne, K., Pastrana, D.V., Garcia, B.A., Buck, C.B., Weitzman, M.D., McBride, A.A., (2021). Histone Modifications in Papillomavirus Virion Minichromosomes. mBio 12. doi 10.1128/mBio.03274-20
Schiller, J., Lowy, D., (2018). Explanations for the high potency of HPV prophylactic vaccines. Vaccine 36, 4768-4773. doi 10.1016/j.vaccine.2017.12.079
Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, H., Ohkawa, Y., Kurumizaka, H., (2017). Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8. Biochemistry 56, 2184-2196. doi 10.1021/acs.biochem.6b01098
Zhang, P., Monteiro da Silva, G., Deatherage, C., Burd, C., DiMaio, D., (2018). Cell-Penetrating Peptide Mediates Intracellular Membrane Passage of Human Papillomavirus L2 Protein to Trigger Retrograde Trafficking. Cell 174, 1465-1476 e1413. doi 10.1016/j.cell.2018.07.031
Zhao, K.N., Sun, X.Y., Frazer, I.H., Zhou, J., (1998). DNA packaging by L1 and L2 capsid proteins of bovine papillomavirus type 1. Virology 243, 482-491. doi 10.1006/viro.1998.9091
