The ELR (Early to Late Region) is the region between the end of the E2 and beginning of the L2 ORF. It is sometimes named NCR2 (Non-Coding Region 2) or URR-2 (Upstream Regulatory Region 2). Many viruses, such as the beta, gamma, mu and pi-papillomaviruses, have either very short or no ELRs. The feline and canine papillomaviruses of the lambda genus have very long (about 1.5kb) ELR regions. The E5 genes, when present, are usually found in the ELR. The early polyadenylation signal is located here.